Nivea Hand Age Defying Q10 Plus Cream. NIVEA Hand Age Defying Q10Plus smoothes hands and visibly reduces the appearance of ageing. The advanced formula is quickly absorbed and contains: the skin’s own coenzyme Q10 which helps support your skin cell’s natural repair function, helping your skin stay visibly smooth and firm. UVA/UVB filters to help prevent the early signs of skin ageing. dermatologically approved. Enjoy younger and smoother looking hands!